2025 Mercedes-Benz S-Class Specs, MPG & Trims
EPA fuel-economy data and specifications for the 2025 Mercedes-Benz S-Class (15–24 MPG combined) across 6 listed configurations.
Overview
- Body class
- Large Cars, Midsize Cars
- Drive
- All-Wheel Drive
- Engine
- 6-cyl, 3.0 L; 12-cyl, 6.0 L; 8-cyl, 4.0 L
- Fuel type
- Premium Gasoline
- Combined MPG
- 15–24 MPG
- Annual fuel cost
- $3,400–$5,500
- Configurations
- 6
MPG & fuel economy
City, highway and combined values below are EPA estimates. Where a powertrain has several configurations, the table shows the lowest–highest reported value. Electric configurations use MPGe.
| Powertrain | City | Highway | Combined | Annual fuel cost | CO2 | Range |
|---|---|---|---|---|---|---|
| 6-cyl 3.0 L · Premium Gasoline · All-Wheel Drive | 20–21 | 29–31 | 23–24 | $3,400–$3,550 | 106–364 g/mi | 470 mi |
| 8-cyl 4.0 L · Premium Gasoline · All-Wheel Drive | 15–17 | 23–27 | 18–20 | $4,100–$4,550 | 305–451 g/mi | 390 mi |
| 12-cyl 6.0 L · Premium Gasoline · All-Wheel Drive | 12 | 20 | 15 | $5,500 | 603 g/mi | — |
Configurations & engine comparison
Each row is one configuration/engine combination reported by the EPA for this model year. Missing EPA values are shown as —.
| Configuration / engine | Drive | Transmission | Cyl. | Displ. (L) | Fuel type | City | Hwy | Comb. | Annual cost |
|---|---|---|---|---|---|---|---|---|---|
| AMG S63 E Performance | All-Wheel Drive | Automatic 9-spd | 8 | 4.0 | Premium Gasoline | 15 | 23 | 18 | $4,550 |
| Maybach S680 4matic | All-Wheel Drive | Automatic 9-spd | 12 | 6.0 | Premium Gasoline | 12 | 20 | 15 | $5,500 |
| S500 4matic | All-Wheel Drive | Automatic 9-spd | 6 | 3.0 | Premium Gasoline | 21 | 31 | 24 | $3,400 |
| S580 4matic | All-Wheel Drive | Automatic 9-spd | 8 | 4.0 | Premium Gasoline | 17 | 25 | 20 | $4,100 |
| S580 4matic Maybach | All-Wheel Drive | Automatic 9-spd | 8 | 4.0 | Premium Gasoline | 16 | 27 | 20 | $4,100 |
| S580e 4matic | All-Wheel Drive | Automatic 9-spd | 6 | 3.0 | Premium Gasoline | 20 | 29 | 23 | $3,550 |
Frequently asked questions
What is the combined MPG of the 2025 Mercedes-Benz S-Class?
According to EPA data, the 2025 Mercedes-Benz S-Class is rated at 15–24 MPG combined for its conventional-fuel configurations.
How many cylinders does the 2025 Mercedes-Benz S-Class have?
The EPA data lists 6, 8, and 12 cylinders across its configurations.
What fuel type does the 2025 Mercedes-Benz S-Class use?
It uses Premium Gasoline.
What is the annual fuel cost of the 2025 Mercedes-Benz S-Class?
The EPA estimates annual fuel costs ranging from $3,400 to $5,500.