2006 Mercedes-Benz S-Class Specs, MPG & Trims
EPA fuel-economy data and specifications for the 2006 Mercedes-Benz S-Class (13–19 MPG combined) across 8 listed configurations.
Overview
- Body class
- Large Cars
- Drive
- Rear-Wheel Drive, 4-Wheel or All-Wheel Drive
- Engine
- 6-cyl, 3.7 L; 8-cyl, 4.3 L; 8-cyl, 5.0 L; 8-cyl, 5.4 L; 12-cyl, 5.5 L; 12-cyl, 6.0 L
- Fuel type
- Premium Gasoline
- Combined MPG
- 13–19 MPG
- Annual fuel cost
- $4,350–$6,300
- Configurations
- 8
MPG & fuel economy
City, highway and combined values below are EPA estimates. Where a powertrain has several configurations, the table shows the lowest–highest reported value. Electric configurations use MPGe.
| Powertrain | City | Highway | Combined | Annual fuel cost | CO2 |
|---|---|---|---|---|---|
| 8-cyl 4.3 L · Premium Gasoline · 4-Wheel or All-Wheel Drive | 15 | 21 | 17 | $4,850 | — |
| 8-cyl 5.0 L · Premium Gasoline · 4-Wheel or All-Wheel Drive | 14 | 20 | 16 | $5,150 | — |
| 6-cyl 3.7 L · Premium Gasoline · Rear-Wheel Drive | 16 | 23 | 18 | $4,550 | — |
| 8-cyl 4.3 L · Premium Gasoline · Rear-Wheel Drive | 16 | 24 | 19 | $4,350 | — |
| 8-cyl 5.0 L · Premium Gasoline · Rear-Wheel Drive | 14 | 22 | 17 | $4,850 | — |
| 8-cyl 5.4 L · Premium Gasoline · Rear-Wheel Drive | 13 | 20 | 16 | $5,150 | — |
| 12-cyl 5.5 L · Premium Gasoline · Rear-Wheel Drive | 11 | 17 | 13 | $6,300 | — |
| 12-cyl 6.0 L · Premium Gasoline · Rear-Wheel Drive | 11 | 18 | 14 | $5,850 | — |
Configurations & engine comparison
Each row is one configuration/engine combination reported by the EPA for this model year. Missing EPA values are shown as —.
| Configuration / engine | Drive | Transmission | Cyl. | Displ. (L) | Fuel type | City | Hwy | Comb. | Annual cost |
|---|---|---|---|---|---|---|---|---|---|
| S350 | Rear-Wheel Drive | Automatic 5-spd | 6 | 3.7 | Premium Gasoline | 16 | 23 | 18 | $4,550 |
| S430 | Rear-Wheel Drive | Automatic 7-spd | 8 | 4.3 | Premium Gasoline | 16 | 24 | 19 | $4,350 |
| S430 4matic | 4-Wheel or All-Wheel Drive | Automatic 5-spd | 8 | 4.3 | Premium Gasoline | 15 | 21 | 17 | $4,850 |
| S500 | Rear-Wheel Drive | Automatic 7-spd | 8 | 5.0 | Premium Gasoline | 14 | 22 | 17 | $4,850 |
| S500 4matic | 4-Wheel or All-Wheel Drive | Automatic 5-spd | 8 | 5.0 | Premium Gasoline | 14 | 20 | 16 | $5,150 |
| S55 AMG | Rear-Wheel Drive | Automatic (S5) | 8 | 5.4 | Premium Gasoline | 13 | 20 | 16 | $5,150 |
| S600 | Rear-Wheel Drive | Automatic 5-spd | 12 | 5.5 | Premium Gasoline | 11 | 17 | 13 | $6,300 |
| S65 AMG | Rear-Wheel Drive | Automatic (S5) | 12 | 6.0 | Premium Gasoline | 11 | 18 | 14 | $5,850 |
Frequently asked questions
What is the combined MPG of the 2006 Mercedes-Benz S-Class?
According to EPA data, the 2006 Mercedes-Benz S-Class is rated at 13–19 MPG combined for its conventional-fuel configurations.
How many cylinders does the 2006 Mercedes-Benz S-Class have?
The EPA data lists 6, 8, and 12 cylinders across its configurations.
What fuel type does the 2006 Mercedes-Benz S-Class use?
It uses Premium Gasoline.
What is the annual fuel cost of the 2006 Mercedes-Benz S-Class?
The EPA estimates annual fuel costs ranging from $4,350 to $6,300.