2021 Mercedes-Benz S-Class Specs, MPG & Trims
EPA fuel-economy data and specifications for the 2021 Mercedes-Benz S-Class (17–24 MPG combined) across 7 listed configurations.
Overview
- Body class
- Subcompact Cars, Compact Cars, Large Cars
- Drive
- Rear-Wheel Drive, 4-Wheel Drive
- Engine
- 8-cyl, 4.0 L; 6-cyl, 3.0 L
- Fuel type
- Premium Gasoline
- Combined MPG
- 17–24 MPG
- Annual fuel cost
- $3,400–$4,850
- Configurations
- 7
MPG & fuel economy
City, highway and combined values below are EPA estimates. Where a powertrain has several configurations, the table shows the lowest–highest reported value. Electric configurations use MPGe.
| Powertrain | City | Highway | Combined | Annual fuel cost | CO2 |
|---|---|---|---|---|---|
| 6-cyl 3.0 L · Premium Gasoline · 4-Wheel Drive | 20 | 29 | 24 | $3,400 | 372 g/mi |
| 8-cyl 4.0 L · Premium Gasoline · 4-Wheel Drive | 14–17 | 24–26 | 17–20 | $4,100–$4,850 | 452–510 g/mi |
| 8-cyl 4.0 L · Premium Gasoline · Rear-Wheel Drive | 16 | 26 | 20 | $4,100 | 454 g/mi |
Configurations & engine comparison
Each row is one configuration/engine combination reported by the EPA for this model year. Missing EPA values are shown as —.
| Configuration / engine | Drive | Transmission | Cyl. | Displ. (L) | Fuel type | City | Hwy | Comb. | Annual cost |
|---|---|---|---|---|---|---|---|---|---|
| AMG S63 4matic Plus Convertible | 4-Wheel Drive | Automatic 9-spd | 8 | 4.0 | Premium Gasoline | 14 | 24 | 17 | $4,850 |
| AMG S63 4matic Plus Coupe | 4-Wheel Drive | Automatic 9-spd | 8 | 4.0 | Premium Gasoline | 16 | 26 | 19 | $4,350 |
| S500 4matic | 4-Wheel Drive | Automatic 9-spd | 6 | 3.0 | Premium Gasoline | 20 | 29 | 24 | $3,400 |
| S560 4matic Coupe | 4-Wheel Drive | Automatic 9-spd | 8 | 4.0 | Premium Gasoline | 16 | 26 | 20 | $4,100 |
| S560 Convertible | Rear-Wheel Drive | Automatic 9-spd | 8 | 4.0 | Premium Gasoline | 16 | 26 | 20 | $4,100 |
| S580 4matic | 4-Wheel Drive | Automatic 9-spd | 8 | 4.0 | Premium Gasoline | 17 | 25 | 20 | $4,100 |
| S580 4matic Maybach | 4-Wheel Drive | Automatic 9-spd | 8 | 4.0 | Premium Gasoline | 16 | 24 | 19 | $4,350 |
Frequently asked questions
What is the combined MPG of the 2021 Mercedes-Benz S-Class?
According to EPA data, the 2021 Mercedes-Benz S-Class is rated at 17–24 MPG combined for its conventional-fuel configurations.
How many cylinders does the 2021 Mercedes-Benz S-Class have?
The EPA data lists 6 and 8 cylinders across its configurations.
What fuel type does the 2021 Mercedes-Benz S-Class use?
It uses Premium Gasoline.
What is the annual fuel cost of the 2021 Mercedes-Benz S-Class?
The EPA estimates annual fuel costs ranging from $3,400 to $4,850.