2022 Mercedes-Benz E-Class Specs, MPG & Trims
EPA fuel-economy data and specifications for the 2022 Mercedes-Benz E-Class (22–26 MPG combined) across 11 listed configurations.
Overview
- Body class
- Midsize Cars, Midsize Station Wagons, Subcompact Cars
- Drive
- 4-Wheel Drive, Rear-Wheel Drive, All-Wheel Drive
- Engine
- 6-cyl, 3.0 L; 4-cyl, 2.0 L
- Fuel type
- Premium Gasoline
- Combined MPG
- 22–26 MPG
- Annual fuel cost
- $3,150–$3,750
- Configurations
- 11
MPG & fuel economy
City, highway and combined values below are EPA estimates. Where a powertrain has several configurations, the table shows the lowest–highest reported value. Electric configurations use MPGe.
| Powertrain | City | Highway | Combined | Annual fuel cost | CO2 |
|---|---|---|---|---|---|
| 6-cyl 3.0 L · Premium Gasoline · 4-Wheel Drive | 20–23 | 27–30 | 22–25 | $3,300–$3,750 | 348–397 g/mi |
| 4-cyl 2.0 L · Premium Gasoline · All-Wheel Drive | 21 | 29 | 24 | $3,400 | 366 g/mi |
| 4-cyl 2.0 L · Premium Gasoline · Rear-Wheel Drive | 23 | 31 | 26 | $3,150 | 342 g/mi |
| 6-cyl 3.0 L · Premium Gasoline · Rear-Wheel Drive | 22 | 29 | 25 | $3,300 | 360 g/mi |
Configurations & engine comparison
Each row is one configuration/engine combination reported by the EPA for this model year. Missing EPA values are shown as —.
| Configuration / engine | Drive | Transmission | Cyl. | Displ. (L) | Fuel type | City | Hwy | Comb. | Annual cost |
|---|---|---|---|---|---|---|---|---|---|
| AMG E53 4matic Plus | 4-Wheel Drive | Automatic 9-spd | 6 | 3.0 | Premium Gasoline | 21 | 29 | 24 | $3,400 |
| AMG E53 4matic Plus Convertible | 4-Wheel Drive | Automatic 9-spd | 6 | 3.0 | Premium Gasoline | 20 | 27 | 22 | $3,750 |
| AMG E53 4matic Plus Coupe | 4-Wheel Drive | Automatic 9-spd | 6 | 3.0 | Premium Gasoline | 20 | 28 | 23 | $3,550 |
| E350 | Rear-Wheel Drive | Automatic 9-spd | 4 | 2.0 | Premium Gasoline | 23 | 31 | 26 | $3,150 |
| E350 4matic | All-Wheel Drive | Automatic 9-spd | 4 | 2.0 | Premium Gasoline | 21 | 29 | 24 | $3,400 |
| E450 4matic | 4-Wheel Drive | Automatic 9-spd | 6 | 3.0 | Premium Gasoline | 23 | 30 | 25 | $3,300 |
| E450 4matic All-Terrain (wagon) | 4-Wheel Drive | Automatic 9-spd | 6 | 3.0 | Premium Gasoline | 21 | 28 | 24 | $3,400 |
| E450 4matic Convertible | 4-Wheel Drive | Automatic 9-spd | 6 | 3.0 | Premium Gasoline | 22 | 29 | 24 | $3,400 |
| E450 4matic Coupe | 4-Wheel Drive | Automatic 9-spd | 6 | 3.0 | Premium Gasoline | 21 | 30 | 24 | $3,400 |
| E450 Convertible | Rear-Wheel Drive | Automatic 9-spd | 6 | 3.0 | Premium Gasoline | 22 | 29 | 25 | $3,300 |
| E450 Coupe | Rear-Wheel Drive | Automatic 9-spd | 6 | 3.0 | Premium Gasoline | 22 | 29 | 25 | $3,300 |
Frequently asked questions
What is the combined MPG of the 2022 Mercedes-Benz E-Class?
According to EPA data, the 2022 Mercedes-Benz E-Class is rated at 22–26 MPG combined for its conventional-fuel configurations.
How many cylinders does the 2022 Mercedes-Benz E-Class have?
The EPA data lists 4 and 6 cylinders across its configurations.
What fuel type does the 2022 Mercedes-Benz E-Class use?
It uses Premium Gasoline.
What is the annual fuel cost of the 2022 Mercedes-Benz E-Class?
The EPA estimates annual fuel costs ranging from $3,150 to $3,750.