2010 Mercedes-Benz E-Class Specs, MPG & Trims

EPA fuel-economy data and specifications for the 2010 Mercedes-Benz E-Class (15–21 MPG combined) across 7 listed configurations.

Overview

Body class
Subcompact Cars, Midsize Cars
Drive
Rear-Wheel Drive, 4-Wheel Drive
Engine
8-cyl, 5.5 L; 6-cyl, 3.5 L; 8-cyl, 6.3 L
Fuel type
Premium Gasoline
Combined MPG
15–21 MPG
Annual fuel cost
$3,900–$5,500
Configurations
7

MPG & fuel economy

City, highway and combined values below are EPA estimates. Where a powertrain has several configurations, the table shows the lowest–highest reported value. Electric configurations use MPGe.

EPA city, highway and combined ratings by powertrain for the 2010 Mercedes-Benz E-Class. Electric configurations are rated in MPGe.
PowertrainCityHighwayCombinedAnnual fuel costCO2
6-cyl 3.5 L · Premium Gasoline · 4-Wheel Drive172419$4,350—
8-cyl 5.5 L · Premium Gasoline · 4-Wheel Drive152318$4,550—
6-cyl 3.5 L · Premium Gasoline · Rear-Wheel Drive17–182620–21$3,900–$4,100—
8-cyl 5.5 L · Premium Gasoline · Rear-Wheel Drive15–1623–2418$4,550—
8-cyl 6.3 L · Premium Gasoline · Rear-Wheel Drive132015$5,500—

Configurations & engine comparison

Each row is one configuration/engine combination reported by the EPA for this model year. Missing EPA values are shown as —.

Every EPA-listed configuration for the 2010 Mercedes-Benz E-Class (7 rows). "Configuration" is the EPA configuration/engine name.
Configuration / engineDriveTransmissionCyl.Displ. (L)Fuel typeCityHwyComb.Annual cost
E350Rear-Wheel DriveAutomatic 7-spd63.5Premium Gasoline182621$3,900
E350 4matic4-Wheel DriveAutomatic 7-spd63.5Premium Gasoline172419$4,350
E350 CoupeRear-Wheel DriveAutomatic 7-spd63.5Premium Gasoline172620$4,100
E550Rear-Wheel DriveAutomatic 7-spd85.5Premium Gasoline162418$4,550
E550 4matic4-Wheel DriveAutomatic 7-spd85.5Premium Gasoline152318$4,550
E550 CoupeRear-Wheel DriveAutomatic 7-spd85.5Premium Gasoline152318$4,550
E63 AMGRear-Wheel DriveAutomatic 7-spd86.3Premium Gasoline132015$5,500

Frequently asked questions

What is the combined MPG of the 2010 Mercedes-Benz E-Class?

According to EPA data, the 2010 Mercedes-Benz E-Class is rated at 15–21 MPG combined for its conventional-fuel configurations.

How many cylinders does the 2010 Mercedes-Benz E-Class have?

The EPA data lists 6 and 8 cylinders across its configurations.

What fuel type does the 2010 Mercedes-Benz E-Class use?

It uses Premium Gasoline.

What is the annual fuel cost of the 2010 Mercedes-Benz E-Class?

The EPA estimates annual fuel costs ranging from $3,900 to $5,500.